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Which of the following lymphoid organs or tissues has the immunological function of filtering pathogens from the blood?


A) lymph nodes
B) thymus
C) spleen
D) GALT
E) tonsils

F) B) and C)
G) C) and D)

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Certain complement components stimulate inflammation and phagocytosis.

A) True
B) False

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Each of the following is involved in the migration of white blood cells except


A) chemotaxis.
B) diapedesis.
C) motility.
D) vasodilatation.
E) phagocytosis.

F) B) and D)
G) A) and B)

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Which of the following is a chemical used by phagocytes to destroy ingested foreign substances?


A) hydrogen peroxide
B) nitric oxide
C) lactic acid
D) superoxide anion
E) All of these are used.

F) B) and E)
G) C) and D)

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B lymphocytes and T lymphocytes mature in the thymus gland.

A) True
B) False

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Nonspecific chemical defenses include


A) lysozyme.
B) lactic acid and electrolytes of sweat.
C) skin's acidic pH and fatty acids.
D) stomach hydrochloric acid.
E) All of the choices are correct.

F) A) and B)
G) C) and D)

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Mario is a 35-year-old male who has come into your ER with a laceration to his left hand. According to Mario, he was working on home renovations in his 1945 city bungalow, when an old board fell from a shelf and injured his hand. The laceration is a cut about 3 inches long, but fairly shallow. It appears that it was bleeding pretty heavily, but he has stopped the bleeding by holding pressure on it with an old t-shirt. He said it happened about an hour ago. -Mario asks you why the laceration is puffy,and has become fairly itchy.What is an accurate response?


A) "This is a normal response to injury.Blood has rushed to the area,fluid is leaking from the damaged vessels,and chemical mediators called cytokines are causing you to itch."
B) "This is a normal response to the injury.Your body is building up pressure around the wound to stop the bleeding,and you're probably itchy because the wood had something on it that you are allergic to."
C) "This is not what I was expecting.I'll call the doctor now to lance the swollen flesh,and in the meantime,I'll apply calamine lotion to the wound."
D) "This is not what I was expecting.Edema and pruritus are early signs of gangrene.I'll have the doctor start you on antibiotics right away.Also,hold your hand above your heart to decrease blood flow to the area."

E) A) and C)
F) A) and B)

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Plasma is also called lymph.

A) True
B) False

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Which of the following is not an event of phagocytosis?


A) diapedesis
B) chemotaxis
C) phagolysosome formation
D) destruction
E) ingestion

F) A) and E)
G) B) and D)

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Diapedesis is the


A) loss of blood due to hemorrhaging.
B) production of only red blood cells.
C) production of white blood cells,red blood cells,and platelets.
D) plugging of broken vessels to stop bleeding.
E) migration of white blood cells from the blood out to the tissues.

F) A) and B)
G) A) and C)

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Keratin is an important aspect of nonspecific defense because it


A) is toxic to pathogens.
B) creates a physical barrier against pathogens.
C) destroys pathogens.
D) physically restricts pathogens to a specific region.
E) None of the choices is correct.

F) B) and D)
G) All of the above

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Endotoxin is an exogenous pyrogen.

A) True
B) False

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When monocytes migrate from the blood out to the tissues they are transformed by inflammatory mediators to develop into


A) primary phagocytes.
B) neutrophils.
C) killer T cells.
D) cytotoxic T cells.
E) macrophages.

F) A) and E)
G) A) and B)

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Which of the following is not a type of phagocyte?


A) neutrophil
B) macrophage
C) Kupffer cell
D) monocyte
E) lymphocyte

F) C) and E)
G) B) and D)

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Which of the following is in the correct order from greatest to least phagocytic activity?


A) neutrophils,eosinophils,macrophages
B) neutrophils,macrophages,eosinophils
C) eosinophils,macrophages,neutrophils
D) macrophages,neutrophils,eosinophils
E) macrophages,eosinophils,neutrophils

F) A) and E)
G) C) and E)

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Histamine,serotonin,and bradykinin are all


A) vasoactive mediators.
B) mediators of B-cell activity.
C) mediators of T-cell activity.
D) mediators that increase chemotaxis.
E) fever inducers.

F) A) and B)
G) All of the above

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Genetic differences among species and within a species can convey genetic immunity to certain diseases.

A) True
B) False

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Which gland shrinks in size during adulthood and has hormones that function in maturation of T lymphocytes?


A) lymph nodes
B) thymus
C) spleen
D) GALT
E) tonsils

F) B) and E)
G) All of the above

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What structures are found along lymphatic vessels and are heavily clustered in the armpit,groin,and neck?


A) lymph nodes
B) thymus
C) spleen
D) GALT
E) tonsils

F) D) and E)
G) A) and B)

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Which of the following is mismatched?


A) interferon alpha and beta - inhibits viral replication
B) interleukin-2 - stimulates T-cell mitosis and B-cell antibody production
C) serotonin - causes smooth muscle contraction
D) prostaglandins - activate eosinophils and B cells
E) tumor necrosis factor - increases chemotaxis and phagocytosis

F) B) and C)
G) B) and D)

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