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The "gold standard" for testing chemical toxicity is laboratory rats and mice.Which of the following is NOT a disadvantage of testing with rodents?


A) Rodent studies are expensive.
B) Rodents have metabolic or physiological differences so the results may not apply to humans.
C) Rodent studies have often involved unrealistically high exposures to the substances being tested.
D) Rodent studies are relatively fast to carry out.

E) A) and B)
F) A) and C)

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Which of the following will have anticarcinogenic activity?


A) aromatic amines, such as β-naphthylamine
B) oncogenes
C) vitamin C, vitamin E, and β-carotene
D) polycyclic aromatic hydrocarbons, such as 3,4-benzopyrene

E) A) and C)
F) A) and B)

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An example of an alkaloid is


A) estradiol.
B) acetic acid.
C) methionine.
D) caffeine.

E) A) and D)
F) A) and C)

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Strong acids and bases can catalyze the hydrolysis of proteins.

A) True
B) False

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Toxicology is the study of ________.

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The carcinogenic hydrocarbons produced during the incomplete burning of organic materials are known as


A) aromatic hydrocarbons.
B) styrene.
C) polycyclic aromatic hydrocarbons.
D) cycloalkanes.

E) A) and B)
F) A) and C)

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People with Alzheimer's disease are deficient in ________.

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Heavy metals act by binding to the -SH groups on enzymes,which makes the enzymes inactive.

A) True
B) False

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An alkaloid is a(n)


A) carcinogen that is made by plants.
B) heterocyclic amine that is occurs naturally in plants.
C) air pollutant.
D) polycyclic aromatic hydrocarbon.

E) B) and C)
F) C) and D)

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The study of the effects of poisons,their detection and identification and their antidotes is known as


A) alkaloidism.
B) carcinogenic testing.
C) berylliosis.
D) toxicology.

E) None of the above
F) A) and D)

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Which of the following corrosive toxins is also called an oxidizing agent?


A) nitric acid
B) hydrochloric acid
C) sodium hydroxide (lye)
D) ozone

E) B) and D)
F) B) and C)

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Which of the following amino acids undergoes oxidation in the presence of photochemical smog?


A) tryptophan
B) glycine
C) leucine
D) threonine

E) All of the above
F) A) and C)

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Name the poison in rosary pea seeds.

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The antidote for mercury poisoning is


A) atropine.
B) nicotine.
C) BAL.
D) coniine.

E) A) and C)
F) A) and B)

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The human body can eliminate half of a dose of mercury poisoning in ________ days.


A) 1
B) 100
C) 70
D) 365

E) A) and D)
F) B) and D)

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The sulfur-containing amino acid cysteine is oxidized to


A) cysteic acid.
B) cysteic sulfoxide.
C) a sulfoxide-carboxylic acid.
D) an amide.

E) B) and D)
F) None of the above

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The LDâ‚…â‚€ value is the amount of a substance that will kill 50% of test animals.

A) True
B) False

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Lead is used in


A) paint.
B) some gasolines.
C) plumbing fixtures.
D) Lead is used in all of the above.

E) B) and C)
F) A) and D)

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Which of the following metals is more hazardous in the vapor state?


A) lead
B) barium
C) mercury
D) cadmium

E) All of the above
F) B) and C)

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Genetics are a leading cause of death from cancer.

A) True
B) False

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