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What is the function of the basal nuclei in normal motor control?


A) They provide a perceptual awareness related to specific sensory inputs from the eyes, nose, and mouth.
B) They provide a general perceptual awareness associated with somatosensory inputs from the skin, muscles, and joints.
C) They provide a sense of the cause-and-effect relationships between muscle actions and the consequences of taking these actions before executing them.
D) They participate in a looping neuronal circuit through which motor impulses are sent to facilitate or suppress movements.
E) They form an initial intention to move, such as when you decide to pick up an object.

F) A) and B)
G) C) and E)

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Practicing a movement allows for "fine-tuning" the original program so that the movement can be executed with fewer corrections.

A) True
B) False

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What is the best description of how a given muscle fiber can be inhibited from contracting?


A) Inhibitory inputs from local reflexes and descending pathways prevent the fiber's motor neuron from firing action potentials.
B) Descending inputs from brainstem components of the middle level of the motor control hierarchy make inhibitory synapses onto the muscle fibers.
C) Contractions in an antagonistic muscle's fibers are stronger than the given muscle's contractions.
D) Golgi tendon organs send afferent neurons directly to muscle fibers that attach to them and release inhibitory neurotransmitter.
E) Interneurons in the local spinal cord region send axons to the muscle fiber's neuromuscular junction, where they impose presynaptic inhibition.

F) C) and E)
G) A) and E)

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The flexor (withdrawal) reflex


A) has a monosynaptic component.
B) is initiated by stretching muscle spindle fibers.
C) is initiated by stimulation of the Golgi tendon organ.
D) stimulates contraction of the ipsilateral flexor muscle and inhibits contraction of the ipsilateral extensor muscle.
E) stimulates contraction of the contralateral flexor muscle and inhibits contraction of the contralateral extensor muscle.

F) C) and D)
G) D) and E)

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In general, the brainstem descending pathways have greater influence over motor neurons controlling muscles involved in fine movements and the corticospinal pathways are more involved in the coordination of large muscle groups and postural muscles.

A) True
B) False

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Which best describes the specific cause of Parkinson disease?


A) enhanced sensitivity of cholinergic receptors to acetylcholine
B) reduced ability of neurons in the substantia nigra to release dopamine
C) failure of serotonin receptors to bind with these neurohormones
D) hyperactivity of metabolic enzymes that degrade dopamine
E) natural tendency of basal nuclei to follow a daily recurring, oscillating cycle of rising and falling norepinephrine release

F) C) and D)
G) C) and E)

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Motor pathways extending from the central nervous system to muscle fibers are subject to control by both excitatory and inhibitory interneurons.

A) True
B) False

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What is the definition of "muscle tone"?


A) the resistance of muscle to continuous passive stretch
B) the sound made by a muscle at rest
C) the maximum contraction strength that a muscle is capable of
D) the tension in a muscle that is only due to the passive resistance of elastic structures
E) the average length of the muscle fibers in a given motor unit

F) B) and C)
G) B) and E)

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According to the hierarchy of motor control,


A) the highest level of control consists entirely of neurons in the primary motor region of the cerebral cortex.
B) the middle level of control does not involve any areas of the cerebral cortex.
C) the local level of control includes the cerebellum and basal nuclei.
D) structures in the middle level receive information from both the higher and the local levels of the hierarchy.
E) afferent information from skin, joint, and muscle receptors cannot modify a movement once it has been initiated by a motor program from the middle level of the hierarchy.

F) B) and C)
G) A) and D)

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The corticospinal pathways:


A) are descending motor pathways.
B) begin in the cortex of the cerebellum.
C) consist of many interneurons linked synaptically.
D) are composed of alpha motor neurons.
E) bring sensory information from the spinal cord to the somatosensory region of the cerebral cortex.

F) A) and B)
G) A) and C)

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Which is a symptom of Parkinson disease?


A) flaccid paralysis
B) intention tremor
C) resting tremor
D) memory loss
E) loss of proprioception

F) A) and B)
G) C) and D)

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Which is TRUE about the function of the cerebellum?


A) It helps to coordinate body movements.
B) It is important in maintaining posture.
C) It receives input from sensory pathways.
D) It stores the memory of motor movements that involve several joints.
E) All of the choices are correct.

F) A) and C)
G) A) and B)

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Once a planned movement is under way, it is usually carried out with no further modifications until it is finished.

A) True
B) False

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The skeletal muscles of the body are represented in the primary motor cortex proportionately to their size.

A) True
B) False

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Sensory neurons that are part of the stretch reflex synapse directly onto the motor neurons of antagonist muscles, and inhibit them.

A) True
B) False

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Crossed-extensor reflexes, but not stretch reflexes, are important postural reflexes.

A) True
B) False

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Which is NOT true about reflexes initiated by muscle spindle activation?


A) They have a monosynaptic component.
B) They result in activation of alpha motor neurons.
C) They result in activation of extrafusal muscle fibers.
D) The "knee-jerk" reflex is an example.
E) They inhibit the activation of muscles that are stretched.

F) None of the above
G) All of the above

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Afferent pathways of the postural reflexes come mainly from:


A) the cerebellum.
B) the eyes, the vestibular apparatus, and the receptors involved in proprioception.
C) muscle spindles and temperature receptors.
D) nociceptors and chemoreceptors.
E) the somatosensory cortex.

F) A) and C)
G) A) and D)

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Inhibitory input to motor neurons is as important for normal muscle function as excitatory input.

A) True
B) False

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When a walking person lifts one foot off of the ground, which of these happens?


A) The body leans so that the center of gravity shifts over the foot that is lifted off the ground.
B) The body only accelerates forward, so the center of gravity remains directy between the two feet.
C) The body accelerates forward, but the center of gravity shifts over the foot that is lifted off the ground.
D) The body leans so that the center of gravity shifts over the foot that is on the ground.
E) The center of mass is left behind by the acceleration of the body, so the body must lean forward to compensate.

F) A) and E)
G) C) and D)

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